A 24-year-old woman presented with
a 12.5 kg weight gain over 6 months (mostly abdominal), hirsutism,
acne, ankle edema,
polydipsia, nocturia, back pain,
pigmentation, poor libido, and lightened menses to our hospital in May 1986.
Peripheral edema had been treated with furosemide and spironolactone for the previous 2 years, and she had stopped the combined oral contraceptive 2 months previously when the referring endocrinologist had suspected
a 12.5 kg weight gain over 6 months (mostly abdominal), hirsutism,
acne, ankle edema,
polydipsia, nocturia, back pain,
pigmentation, poor libido, and lightened menses to our hospital in May 1986.
Peripheral edema had been treated with furosemide and spironolactone for the previous 2 years, and she had stopped the combined oral contraceptive 2 months previously when the referring endocrinologist had suspected
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